Review and information - QUETIAPINE

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Quetiapine (Seroquel) is used for treating schizophrenia or bipolar disorder. It may also be used for other conditions as determined by your doctor.

How to use

Use Quetiapine (Seroquel) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Quetiapine (Seroquel) by mouth with or without food.
Taking Seroquel at the same time each day will help you remember to take it.
Take Quetiapine (Seroquel) on a regular schedule to get the most benefit from it.
It may take a few weeks for you to notice the benefits of Seroquel . Continue to take Seroquel even if you feel well. Do not miss any doses.
Drug Class and Mechanism

Quetiapine (Seroquel) is an antipsychotic. It works by altering the balance of certain chemicals that occur naturally in the brain, which are responsible for thinking and behavior.

Missed Dose

If you miss a dose of Quetiapine (Seroquel) , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.


Store Quetiapine (Seroquel) at 77 degrees F (25 degrees C). Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Seroquel out of the reach of children and away from pets.


Do not use Quetiapine (Seroquel) if:

you are allergic to any ingredient in Seroquel.
Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Seroquel . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you or a family member has a history of bipolar disorder (manic depression), suicidal thoughts or attempts, mental or mood problems, or diabetes
if you drink alcohol or have a history of alcohol or substance abuse
if you have Alzheimer disease, dementia, or trouble swallowing, or you are very overweight
if you have a history of heart problems (eg, heart attack, heart failure, irregular heartbeat), stroke, blood vessel problems, high blood cholesterol levels, or high or low blood pressure
if you have history of blood problems (eg, low white blood cells), liver problems, thyroid problems, cataracts, narrow-angle glaucoma, seizures, neuroleptic malignant syndrome (NMS), high blood prolactin levels, or breast cancer

Some MEDICINES MAY INTERACT with Seroquel . Tell your health care provider if you are taking any other medicines, especially any of the following:
Alpha-blockers (eg, doxazosin) or medicine for high blood pressure because the risk of low blood pressure and fainting may be increased
Azole antifungals (eg, ketoconazole), fluvoxamine, macrolide antibiotics (eg, erythromycin), or telithromycin because they may increase the risk of Seroquel 's side effects
Barbiturates (eg, phenobarbital), carbamazepine, corticosteroids (eg, prednisone), phenytoin, rifampin, or thioridazine because they may decrease Seroquel 's effectiveness
Dopamine receptor agonists (eg, pramipexole) or levodopa because their effectiveness may be decreased by Seroquel

Possible Side Effects

Check with your doctor if any of these most common side effects persist or become bothersome:

agitation; back pain; constipation; dizziness; drowsiness; dry mouth; headache; indigestion; runny nose; sore throat; stomach pain; weakness; weight gain.
Seek medical attention right away if any of these severe side effects occur:
severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); altered mental abilities, including lack of response to your surroundings; high blood sugar (eg, thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, or fruity breath odor); increased or irregular heartbeat; involuntary, uncontrolled muscle movements; lightheadedness when rising from a seated or lying position; muscle stiffness; sweating; tremor; unexplained fever; vision changes.
More Information

Quetiapine (Seroquel) is to be used only by the patient for whom it is prescribed. Do not share it with other people.

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